Electronic Prescribing (eRx) and EPCS sign up with ID.me identity verification

Electronic prescribing (eRx) and electronic prescribing of controlled substances (EPCS) are highly regulated clinical processes and as a result, it is necessary to include security protocols to ensure that the services are only accessed by appropriately credentialed medication professionals. The Drug Enforcement Administration (DEA) mandated a NIST 800-63 certified identity proofing and authentication process for physicians issuing prescriptions of controlled substances online.Throughout the eRx and EPCS verification process, Practice Fusion utilizes ID.me, a secure identity verification service, to help authenticate the identity of every client who prescribes through Practice Fusion. ID.me is a trusted digital identity network that allows hospital systems and EHRs to comply with eRx and EPCS. ID.me is also the first credential service provider in the United States to become NIST-800-63-3 certified. Read the guidelines below to sign up for eRx and/or EPCS using ID.me.   

To get started in the verification process, you will need: 

  1. Your medical credentials 

  • State medical license 
  • NPI (personal) 
  • DEA number (required for EPCS) 
  1. Access to a smartphone for multi-factor authentication 

  • You will need a smartphone that can receive text messages, download apps, and take photos. 

  1. A valid government photo ID or the ability to answer security questions based on your credit history 

  • This includes a driver’s license, state ID card, or a passport 

What does the verification process with ID.me entail? 

  1. You will need to confirm your email address with ID.me 

  • During the signup process, you will be prompted to connect your Practice Fusion login email address to ID.me You will then need to open a new tab to check your inbox for an email from ID.me to confirm your email address. If you need to change your email address, you will have the option to do so. After confirming your email, you will return to the original tab to continue the ID.me verification process. 

  1. Secure your account and set up the ID.me Authenticator app on your phone as your required multi-factor authentication 

  • From your smartphone’s application store, download the ID.me Authenticator app (see Figure 1 below). You will use this app set up your two-factor authentication (2FA). This is a requirement for EPCS as the app will be linked to your EPCS account. It is used to generate a time sensitive push notification or code that is used to both confirm changes to e-signing controls and is also used to e-sign prescriptions for controlled substances.  

  1. Verify your personal details 

  • Enter your address, phone number, and social security number as it appears on your credit report. Your personal information will only be used to verify your identity.  

  1. Verify your identity 

  • You can choose from four different methods to verify your identity (see Figure 2 below). You can answer security questions based on your credit history or upload a photo of a government ID along with a photo of yourself to verify your identity

Figure 1. Download ID.me Authenticator app 


Figure 2. Methods of verification 


What’s new? 

What’s the same? 

  • More options for identity verification 
  • Ability to upload valid forms of identification for identity verification 
  • Faster identity verification process because there is no need for a mailed code to verify address 
  • Option to use app with a simple push notification for two-factor authentication 
  • ID.me provides support here  
  • For eRx enablement, your medical credentials must still be validated 
  • As required by the DEA, you must still request EHR permissions for prescribing controlled substances 
  • For EPCS, you must have the app for two-factor authentication 

Electronic Prescribing (eRx) sign up 
For a more detailed step-by-step guide on how to sign up for eRx, click here.  

Electronic Prescribing of Controlled Substances (EPCS) 
For a more detailed step-by-step guide on how to sign up for EPCS, click here. If you have previously gone through identity verification with ID.me through eRx enablement, you will not need to complete verification steps again. However, you must download the ID.me Authenticator app as a requirement for EPCS. You will still need to request EHR permissions for prescribing controlled substances. For more a more detailed step-by-step guide with screenshots on how to set up EPCS e-signing permissions, click here.


  1. How do I sign up for eRx (e-Prescribing)?
  2. How do I send an eRx (e-Prescription)?
  3. How do I process eRx (e-Prescribing) refill requests?
  4. How do I prescribe multiple medications in a single order?
  5. How do I search for a pharmacy or enter a preferred pharmacy?
  6. Why am I unable to send an eRx (e-Prescription)?
  7. What do eRx (e-Prescribing) error messages mean?
  8. Activating e-prescribing of controlled substances (EPCS): Step 1 of 2
  9. Setting up EPCS e-signing permissions: Step 2 of 2
  10. How do I send e-prescriptions (eRx) and approve refills for controlled substances?
  11. How do I enable and use prescription task delegation?
  12. How do I print and format prescriptions?
  13. What is the status of my eRx (e-Prescribing) request?
  14. Prescription Formulary FAQ's
  15. How do I edit my Drug-Drug and Drug-Allergy Interactions Settings?
  16. How do I add my NPI and DEA numbers to printed prescriptions?
  17. Can I be enabled for e-prescribing on two Practice Fusion accounts at the same time?
  18. How do I edit a refill sent by the pharmacy?
  19. Can I e-Prescribe through multiple eRx vendors?
  20. How do I add a pharmacy to the database?
  21. How can I discontinue a medication?
  22. How can you see the status of an eRx (e-Prescription)?
  23. How does I-STOP affect my practice and what is Practice Fusion doing to prepare for EPCS?
  24. What does the eRx (e-Prescribing) "Pending" status mean?
  25. How do I disable my e-prescribing with Practice Fusion?
  26. How do I re-activate eRx (e-Prescribing)?
  27. How can I help a provider verify eRx (e-Prescribing) credentials?
  28. How can I disable refill requests?
  29. How do I update my phone or fax number for eRx (e-Prescribing)?
  30. Who can send an e-prescription?
  31. Why am I not receiving eRx (e-Prescribing) refills?
  32. What if I fail e-Prescribing (eRx) verification?
  33. How do I use eCoupons?
  34. How do I use electronic prior authorizations?
  35. How do I print an e-Prescription receipt?
  36. How do I use medication adherence?
  37. Why am I receiving an alert to update my medical license?
  38. How can I see medication costs and cost-saving alternatives?
  39. What does it mean when a patient medication is no longer available?
  40. Ohio Prescription Instructions
  41. How does the Maine EPCS Opiates Mandate under L.D. 1646 affect my practice?
  42. How do I initiate a request for a prior authorization from the EHR?
  43. How do I submit prior authorizations via Physicians’ Desk Reference (PDR)?
  44. How do I update the ID.me Authenticator application for EPCS?
  45. Electronic Prescribing (eRx) and EPCS sign up with ID.me identity verification

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