How do I send an eRx (e-Prescription)?

Note: Access to the EHR features described in this article may differ for practices who have already purchased a Practice Fusion EHR subscription plan. Please contact Practice Fusion Customer Service for additional information.

With electronic prescribing, orders are delivered directly to the pharmacy’s computer system, which can help you spend less time calling pharmacies to clarify orders and more time with your patients. Practice Fusion also offers features to help expedite the e-prescribing workflow, such as preferred pharmacy entry and prescription task delegation.

You can add a medication and create an e-prescription from multiple places in the patient chart, including:

  • The Summary tab
  • The medication table in an encounter
  • The Plan section of an encounter
  • A lab result 

Record a medication and e-prescribe during an encounter
1. To add a new medication to the Plan section of an encounter and send an e-prescription, click New Encounter or open an existing encounter. Scroll to Plan section and click Record.


2. Select the Medications tab to add a medication from your Frequent medication list or the patient’s medication list. The medication will first be attached to the encounter. Once attached, click on the medication name to create a new prescription.


3. Alternatively, select Record to add a new medication. Type the first few letters of the medication name to search. The most common route, strength, and form will appear at the top of the list. The search results will display both generic and brand choices, based on the active ingredient of the drug you searched for.


4. After selecting a medication, enter the SIG. Click Enter Shorthand to choose from a list of the most common SIGs for the medication you selected or type in the free-text field below. If using the free text field, confirm the SIG is complete and consistent with other aspects of the prescription order, such as appropriate dose medication for the prescribed medication, to prevent processing delays.


5. You may associate a diagnosis from the patient’s chart and enter a start date. To discontinue the medication at a later date, you may also enter a future stop date. For additional information about discontinuing medications, click here. If needed, enter a comment for the medication or encounter. Select Medline Plus or Patient education materials to print resources related to the medication.

Click Done to simply add the medication to the encounter or select Order to begin creating a new prescription.

6. Review the patient’s drug formulary and any drug interaction or drug allergy alerts if present. When required, a prior authorization notification will also display.

From this screen, you can add additional medications to the order using the Search for new medication field at the top of the order. For more information, see: How do I prescribe multiple medications in a single order?


7. Click Next to enter the dispense quantity, unit, and number of refills. Although you may send a custom note to the pharmacy using the Note to pharmacy field, this field should not contain redundant or conflicting information that has already been entered as part of the prescription. You may also record an internal Rx comment for your own reference. Note: If you have previously prescribed the medication for this patient, the SIG, quantity, unit, days supply, and number of refills will automatically be pre-populated. You may also use the fly-out pane to review the patient's recent prescription details.


8. Click Next to complete order summary. Practice Fusion will automatically display eCoupon notifications for eligible medications here. From this screen, you will also select the pharmacy. The default pharmacy will be the patient’s preferred pharmacy (if entered) or the patient’s most recently used pharmacy. Open the fly-out pane to see all pharmacies you’ve previously selected for the patient.

9. To search for a new pharmacy, click Change or the pencil icon. You can narrow your search with the provided filters, then search for the pharmacy by typing the first few letters of the pharmacy name or the zip code. You can also use the facility address or patient address buttons to easily find pharmacies close to either location, or utilize Additional search options. Once you’ve found the desired pharmacy, click Select. For detailed instructions on searching for a pharmacy or selecting a preferred pharmacy, click here.


10. Review and confirm all script details. If applicable law requires you to identify the Supervising provider, please select from the drop-down menu. Note: Only providers who are active in the EHR and enabled for e-prescribing will be displayed in the drop down.


11. Click Send eRx to send the e-prescription to the pharmacy. Alternatively, select the down arrow to print or record the prescription. Practice members who have been granted the ability to create prescription drafts can select the prescribing provider and save a draft of the prescription for the provider to complete at a later time. The Save button will be available on every screen of the prescribing workflow.

Status of an eRx
You can review all e-prescriptions for a patient in their Timeline, including the pharmacy details, prescriber and status. 

If a practice member has created a draft for a prescribing provider to complete, it will accessible in the Timeline when filtering by Prescription drafts.

Error Messages
You could encounter an error message when trying to send an eRx. The most common errors can be resolved by adding missing information to the patient Profile (i.e. zip code and address). The provider will also need to have a valid NPI number entered in their user profile to send an eRx. The practice admin can enter this by clicking Settings in the top-right corner of the EHR, then selecting Users. Click on the provider’s name to open their profile, enter their NPI number, and click Save.

For additional information, please see:


  1. How do I sign up for eRx (e-Prescribing)?
  2. How do I send an eRx (e-Prescription)?
  3. How do I process eRx (e-Prescribing) refill requests?
  4. How do I prescribe multiple medications in a single order?
  5. How do I search for a pharmacy or enter a preferred pharmacy?
  6. Why am I unable to send an eRx (e-Prescription)?
  7. What do eRx (e-Prescribing) error messages mean?
  8. Activating e-prescribing of controlled substances (EPCS): Step 1 of 2
  9. Setting up EPCS e-signing permissions: Step 2 of 2
  10. How do I send e-prescriptions (eRx) and approve refills for controlled substances?
  11. How do I enable and use prescription task delegation?
  12. How do I print and format prescriptions?
  13. What is the status of my eRx (e-Prescribing) request?
  14. Prescription Formulary FAQ's
  15. How do I edit my Drug-Drug and Drug-Allergy Interactions Settings?
  16. How do I add my NPI and DEA numbers to printed prescriptions?
  17. Can I be enabled for e-prescribing on two Practice Fusion accounts at the same time?
  18. How do I edit a refill sent by the pharmacy?
  19. Can I e-Prescribe through multiple eRx vendors?
  20. How do I add a pharmacy to the database?
  21. How can I discontinue a medication?
  22. How can you see the status of an eRx (e-Prescription)?
  23. How does I-STOP affect my practice and what is Practice Fusion doing to prepare for EPCS?
  24. What does the eRx (e-Prescribing) "Pending" status mean?
  25. How do I disable my e-prescribing with Practice Fusion?
  26. How do I re-activate eRx (e-Prescribing)?
  27. How can I help a provider verify eRx (e-Prescribing) credentials?
  28. How can I disable refill requests?
  29. How do I update my phone or fax number for eRx (e-Prescribing)?
  30. Who can send an e-prescription?
  31. Why am I not receiving eRx (e-Prescribing) refills?
  32. What if I fail e-Prescribing (eRx) verification?
  33. How do I use eCoupons?
  34. How do I use electronic prior authorizations?
  35. How do I print an e-Prescription receipt?
  36. How do I use medication adherence?
  37. Why am I receiving an alert to update my medical license?
  38. How can I see medication costs and cost-saving alternatives?
  39. What does it mean when a patient medication is no longer available?
  40. Ohio Prescription Instructions
  41. How does the Maine EPCS Opiates Mandate under L.D. 1646 affect my practice?
  42. How do I initiate a request for a prior authorization from the EHR?
  43. How do I submit prior authorizations via Physicians’ Desk Reference (PDR)?
  44. How do I update the Authenticator application for EPCS?
  45. Electronic Prescribing (eRx) and EPCS sign up with identity verification

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