Why am I unable to send an eRx (e-Prescription)?

Note: Access to the EHR features described in this article may differ for practices who have already purchased a Practice Fusion EHR subscription plan. Please contact Practice Fusion Customer Service for additional information.

If you do not have the option to send a prescription electronically, we recommend checking the following:

  • Your username has been enabled for e-prescribing

  • You are sending a prescription for an actual patient rather than a test patient
  • The patient has completed demographic information

  • All prescription information is properly entered

  • Your NPI number is properly entered in your User Profile
  • Your DEA number is properly entered in your User Profile

1. Confirm that the username you are logged in with is enabled for e-prescribing in Practice Fusion. You can check your enablement status on the
e-Prescribing tile of your Practice Dashboard.

2. You cannot send an e-script for a test patient. Ensure that the patient in question is an actual patient with a chart created in Practice Fusion. 

3. Ensure that the patient has a valid date of birth, phone number, and address entered in their Profile.

4. Ensure that the SIG and other details are entered for the prescription. Missing information will be highlighted in red for you to correct:

5. Confirm that your NPI number is entered in your User Profile. An alert will appear at the top of the order if your NPI is not entered.

administrator may edit your NPI number by clicking the Settings icon, then Users tab. Select your name to edit and enter your NPI number. For additional information, please see: How do I edit a user's profile?

6. Ensure that your DEA number is entered and formatted correctly in your User Profile. Any administrator may edit your NPI number by clicking the Settings icon, then Users tab. Select your name to edit your DEA number.

*Note: You cannot e-prescribe custom medications. These medications can be recorded and printed, then faxed manually to the pharmacy or handed to the patient to fill in person. Additionally, you may not e-prescribe controlled substances unless you have activated EPCS.


  1. How do I sign up for eRx (e-Prescribing)?
  2. How do I send an eRx (e-Prescription)?
  3. How do I process eRx (e-Prescribing) refill requests?
  4. How do I prescribe multiple medications in a single order?
  5. How do I search for a pharmacy or enter a preferred pharmacy?
  6. Why am I unable to send an eRx (e-Prescription)?
  7. What do eRx (e-Prescribing) error messages mean?
  8. Activating e-prescribing of controlled substances (EPCS): Step 1 of 2
  9. Setting up EPCS e-signing permissions: Step 2 of 2
  10. How do I send e-prescriptions (eRx) and approve refills for controlled substances?
  11. How do I enable and use prescription task delegation?
  12. How do I print and format prescriptions?
  13. What is the status of my eRx (e-Prescribing) request?
  14. Prescription Formulary FAQ's
  15. How do I edit my Drug-Drug and Drug-Allergy Interactions Settings?
  16. How do I add my NPI and DEA numbers to printed prescriptions?
  17. Can I be enabled for e-prescribing on two Practice Fusion accounts at the same time?
  18. How do I edit a refill sent by the pharmacy?
  19. Can I e-Prescribe through multiple eRx vendors?
  20. How do I add a pharmacy to the database?
  21. How can I discontinue a medication?
  22. How can you see the status of an eRx (e-Prescription)?
  23. How does I-STOP affect my practice and what is Practice Fusion doing to prepare for EPCS?
  24. What does the eRx (e-Prescribing) "Pending" status mean?
  25. How do I disable my e-prescribing with Practice Fusion?
  26. How do I re-activate eRx (e-Prescribing)?
  27. How can I help a provider verify eRx (e-Prescribing) credentials?
  28. How can I disable refill requests?
  29. How do I update my phone or fax number for eRx (e-Prescribing)?
  30. Who can send an e-prescription?
  31. Why am I not receiving eRx (e-Prescribing) refills?
  32. What if I fail e-Prescribing (eRx) verification?
  33. How do I use eCoupons?
  34. How do I use electronic prior authorizations?
  35. How do I print an e-Prescription receipt?
  36. How do I use medication adherence?
  37. Why am I receiving an alert to update my medical license?
  38. How can I see medication costs and cost-saving alternatives?
  39. What does it mean when a patient medication is no longer available?
  40. Ohio Prescription Instructions
  41. How does the Maine EPCS Opiates Mandate under L.D. 1646 affect my practice?
  42. How do I initiate a request for a prior authorization from the EHR?
  43. How do I submit prior authorizations via Physicians’ Desk Reference (PDR)?
  44. How do I update the ID.me Authenticator application for EPCS?
  45. Electronic Prescribing (eRx) and EPCS sign up with ID.me identity verification

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